Maitake

Botanical name: Grifola frondosa

Parts used and where grown

Maitake is a very large mushroom, which grows deep in the mountains of northeastern Japan, as well as in North America and Europe. Famous for its taste and health benefits, maitake is also known as the “dancing mushroom.”¹ Legend holds that those who found the rare mushroom began dancing with joy. Others attribute its name to the way the fruit bodies of the mushroom overlap each other, giving the appearance of dancing butterflies.

Maitake is extremely sensitive to environmental changes, which have presented many challenges to those cultivating this mushroom. However, Japanese farmers have succeeded in producing high-quality organic maitake mushrooms, allowing for wider availability both in Japan and the U.S. The fruiting body and mycelium of maitake are used medicinally.

Maitake has been used in connection with the following conditions (refer to the individual health concern for complete information):

Science Ratings	Health Concerns
	High cholesterol and high triglyceride levels HIV support Immune function Infection
Reliable and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit. For a herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit.

Science Ratings

Health Concerns

High cholesterol and high triglyceride levels

HIV support

Immune function

Infection

Reliable and relatively consistent scientific data showing a substantial health benefit.
2Stars

Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
1Star

For a herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit.

Historical or traditional use (may or may not be supported by scientific studies)

Historically, maitake has been used as a tonic and adaptogen (a substance that invigorates or strengthens the system). Along with other “medicinal” mushrooms, such as shiitake and reishi, maitake was used as a food to help promote wellness and vitality.

Active constituents

A common denominator among some mushrooms and some herbs is the presence of complex polysaccharides in their structure. These active constituents help support immune system function and are sometimes called immunomodulators. The polysaccharides present in maitake have a unique structure and are among the most powerful studied in test tubes to date.² The primary polysaccharide, beta-D-glucan, is well absorbed when taken orally and is being studied as a potential tool for prevention and treatment of cancer and as a adjunctive treatment for HIV infection.³ ⁴ Animal studies suggest maitake may lower serum cholesterol and triglycerides.⁵ ⁶ However, this research is still preliminary and requires human trials for confirmation.

How much is usually taken?

Maitake can be used as a food or tea and is also available as a capsule or tablet containing the entire fruiting body of the mushroom. For maitake, the fruit body is higher in polysaccharides than the mycelium, which is why it is recommended. Whole-mushroom maitake supplements, 3–7 grams per day, can be taken.⁷ Liquid maitake extracts with variable concentrations of polysaccharides are available, and should be taken as directed.

Are there any side effects or interactions?

Used as recommended above, there have been no reports of side effects with maitake.

At the time of writing, there were no well-known drug interactions with maitake.

References

1. Hobbs C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995, 110–5.

2. Nanba H, Hamaguchi AM, Kuroda H. The chemical structure of an antitumor polysaccharide in fruit bodies of Grifola frondosa (maitake). Chem Pharm Bull 1987;35:1162–8.

3. Yamada Y, Nanba H, Kuroda H. Antitumor effect of orally administered extracts from fruit body of Grifola frondosa (maitake). Chemotherapy 1990;38:790–6.

4. Nanba H. Immunostimulant activity in vivo and anti-HIV activity in vitro of 3 branched b-1–6-glucans extracted from maitake mushrooms (Grifola frondosa). VIII International Conference on AIDS, Amsterdam, 1992 [abstract].

5. Kubo K, Nanba H. Anti-hyperliposis effect of maitake fruit body (Grifola frondosa). I. Biol Pharm Bull 1997;20:781–5.

6. Adachi K, Nanba H, Otsuka M, Kuroda H. Blood pressure lowering activity present in the fruit body of Grifola frondosa (maitake). Chem Pharm Bull 1988;36:1000–6.

7. Hobbs C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995, 110–5.

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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or chemist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires August 2007.