Calcium D-Glucarate

Calcium D-glucarate

Also indexed as: D-Glucarate, D-Glucaric Acid, Glucaric Acid

Calcium D-glucarate is the calcium salt of D-glucaric acid, a natural substance found in many fruits and vegetables.

Where is it found?

Calcium D-glucarate is available in capsules and tablets. Foods high in glucaric acid (a form of calcium D-glucarate) include apples, Brussel sprouts, broccoli, cabbage, and bean sprouts.¹

Calcium D-glucarate has been used in connection with the following conditions (refer to the individual health concern for complete information):

Science Ratings	Health Concerns
	Cancer
Reliable and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit. For a herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit.

Who is likely to be deficient?

Calcium D-glucarate is not an essential nutrient, and thus no deficiency state exists.

How much is usually taken?

Manufacturers of calcium D-glucarate recommend a daily intake of 200 to 400 mg.

Are there any side effects or interactions?

No side effects have been reported with calcium D-glucarate. Although there are no known drug interactions, many drugs (especially hormones) are metabolized in the liver by binding to glucuronic acid. It is therefore possible that taking calcium D-glucarate could increase the elimination of certain drugs or hormones from the body, thereby reducing their effectiveness. If you are taking any prescription medication, please consult your physician or chemist before taking calcium D-glucarate.

At the time of writing, there were no well-known drug interactions with calcium D-glucarate.

References

1. Dwivedi C, Heck WJ, Downie AA, et al. Effect of calcium glucarate on beta-glucuronidase activity and glucarate content of certain vegetables and fruits. Biochem Med Metab Biol 1990;43:83–92.

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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or chemist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires August 2007.