Chitosan

Chitosan is a polysaccharide found in the shells of crustaceans.

Where is it found?

Chitosan is extracted from the shells of crustaceans, such as shrimp and crab.

Chitosan has been used in connection with the following conditions (refer to the individual health concern for complete information):

Science Ratings	Health Concerns
	High cholesterol Kidney failure Weight loss
Reliable and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit. For a herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit.

Science Ratings

Health Concerns

High cholesterol

Kidney failure

Weight loss

Reliable and relatively consistent scientific data showing a substantial health benefit.
2Stars

Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
1Star

For a herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit.

Who is likely to be deficient?

Chitosan is not an essential nutrient, so deficiencies do not occur.

How much is usually taken?

Most human research has used 3–6 grams per day with meals.

Are there any side effects or interactions?

While no long-term studies of the effects of chitosan on human health have been done, animal studies suggest that this compound could inhibit the absorption of minerals and fat-soluble vitamins. Adverse effects on the growth of children and on the outcome of pregnancy are also possible.¹ In addition, although chitosan-included alterations in intestinal flora are believed to be beneficial, the possibility that these changes may have negative long-term consequences has not been ruled out. People with intestinal malabsorption syndromes should not use chitosan.

At the time of writing, there were no well-known drug interactions with chitosan.

References

1. Koide SS. Chitin-chitosan: properties, benefits and risks. Nutr Res 1998;18:1091–101 [review].

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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or chemist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires August 2007.