Gamma Oryzanol

Gamma oryzanol is a naturally occurring mixture of plant chemicals called sterols and ferulic acid esters.

Where is it found?

Gamma oryzanol is a natural component of rice bran, corn, and barley oils. Gamma oryzanol is also available as a supplement.

Gamma oryzanol has been used in connection with the following condition (refer to the individual health concern for complete information):

Science Ratings	Health Concerns
	Gastritis
	Athletic performance
Reliable and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit. For a herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit.

Who is likely to be deficient?

Since gamma oryzanol is not an essential nutrient, it is not associated with a deficiency state.

How much is usually taken?

Much of the human research with gamma oryzanol used 300 mg per day. Healthy people do not appear to need this supplement.

Are there any side effects or interactions?

Some research suggests that gamma oryzanol taken in moderately high amounts (up to 600 mg per day) for a few months can cause dry mouth, sleepiness, hot flushes, irritability, and light headedness in some individuals.¹

At the time of writing, there were no well-known drug interactions with gamma oryzanol.

References

1. 34. Takemoto T, Miyoshi H, Nagashima H. Clinical trial of Hi-Z fine granules (gamma-oryzanol) on gastrointestinal symptoms at 375 hospitals (Japan). Shinyaku To Rinsho 1977;26 [in Japanese].

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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or chemist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires August 2007.