Methoxyisoflavone

Also indexed as: 5-Methyl-7-Methoxy-Isoflavone

Methoxyisoflavone is a member of the family of flavonoids (isoflavones). In a U.S. patent, the developers of this substance claim, based on preliminary animal research, that it possesses muscle-building and bone-building (anabolic) effects without the side effects seen with either androgenic (male) hormones or oestrogenic (female) hormones.¹

Where is it found?

A few substances similar to methoxyisoflavone are found in many plants and some foods, including soybeans. Whether methoxyisoflavone itself is found in nature is unknown.

Methoxyisoflavone has been used in connection with the following conditions (refer to the individual health concern for complete information):

Science Ratings	Health Concerns
	Athletic performance
Reliable and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit. For a herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit.

Who is likely to be deficient?

Methoxyisoflavone is not an essential nutrient, so no deficiencies are possible.

How much is usually taken?

Manufacturers of methoxyisoflavone recommend 200 to 400 mg twice a day.

Are there any side effects or interactions?

Hormones with anabolic effects on muscle often have side effects that include acne, male-pattern baldness, prostate enlargement, and lower high-density lipoprotein (HDL; “good”) cholesterol. Whether methoxyisoflavone can cause these side effects has not been investigated.

At the time of writing, there were no well-known drug interactions with methoxyisoflavone .

References

1. Feuer L, Farkas L, Nogradi M, et al. Metabolic 5-methyl-isoflavone-derivatives, process for the preparation thereof and compositions containing the same. United States Patent 4,163,746, August 7, 1979.

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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or chemist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires August 2007.