N-Acetyl-Glucosamine

N-acetyl-glucosamine (NAG) is a form of glucosamine, one of the building blocks of joint tissue and other connective tissues. NAG differs from glucosamine sulphate and glucosamine hydrochloride; instead of a sulphur or chloride molecule, NAG has a larger, more complex molecule attached to it. As a result, NAG is an entirely different molecule than either glucosamine sulphate or hydrochloride, and it also appears to be handled by the body differently.

Where is it found?

NAG is available primarily in tablets and capsules.

Who is likely to be deficient?

As NAG is not an essential nutrient, no deficiency states have been reported.

How much is usually taken?

Most manufacturers recommend supplementation with 1,500 mg daily.

Are there any side effects or interactions?

No significant side effects or interactions have yet been reported in studies on NAG.

At the time of writing, there were no well-known drug interactions with N-acetyl-glucosamine.

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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or chemist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires August 2007.